Application
A. Western blot analysis on fetal brain lysate anti-IHH RabMAb (Cat. #AJ1404a).Application
B. Immunohistochemical staining of paraffin-embedded human fetal colon using anti-IHH RabMAb (Cat. #AJ1404a).| Product Name | Indian Hedgehog Antibody (IHH) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IHH, Indian hedgehog protein C-product, HHG-2 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1192Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | IHH Indian hedgehog protein C-product HHG-2 |
|---|---|
| Molecular Weight(MW) | 45251 Da |
| Function | Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity) |
| Tissue Specificity | Expressed in embryonic lung, and in adult kidney and liver |
| Cellular Localization | Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side (By similarity) Note=The N-terminal peptide remains associated with the cell surface (By similarity) |
| Entrez Gene | 3549 |
|---|
Application
A. Western blot analysis on fetal brain lysate anti-IHH RabMAb (Cat. #AJ1404a).
Application
B. Immunohistochemical staining of paraffin-embedded human fetal colon using anti-IHH RabMAb (Cat. #AJ1404a).| Application Notes | WB:1:1000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
