Application
INPP5B Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the INPP5B antibody detected the INPP5B protein (arrow).Application
INPP5B antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the INPP5B antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
INPP5B Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | INPP5B Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | INPP5B; OCRL2; Type II inositol 1, 4, 5-trisphosphate 5-phosphatase; 75 kDa inositol polyphosphate-5-phosphatase; Phosphoinositide 5-phosphatase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | OCRL2 |
|---|---|
| Alternative Names | INPP5B OCRL2 Type II inositol 1 4 5-trisphosphate 5-phosphatase 75 kDa inositol polyphosphate-5-phosphatase Phosphoinositide 5-phosphatase |
| Molecular Weight(MW) | 112852 Da |
| Function | Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events |
| Tissue Specificity | Platelets. |
| Cellular Localization | Cytoplasm, cytosol. Endoplasmic reticulum- Golgi intermediate compartment. Early endosome membrane. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane (By similarity). Golgi apparatus |
| Entrez Gene | 3633 |
|---|---|
| Nucleotide Accession | NP_005531.2 |
Application
INPP5B Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the INPP5B antibody detected the INPP5B protein (arrow).
Application
INPP5B antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the INPP5B antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
INPP5B Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
