Application
INMT Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the INMT antibody detected INMT protein (arrow).Application
INMT Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the INMT Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | INMT Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | INMT; Indolethylamine N-methyltransferase; Aromatic alkylamine N-methyltransferase; Thioether S-methyltransferase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | INMT Indolethylamine N-methyltransferase Aromatic alkylamine N-methyltransferase Thioether S-methyltransferase |
|---|---|
| Molecular Weight(MW) | 28891 Da |
| Function | Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2- methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide Plays an important role in the detoxification of selenium compounds (By similarity). Catalyzes the N-methylation of tryptamine and structurally related compounds |
| Tissue Specificity | Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult and fetal kidney and liver, in adult spleen, thymus, ovary, colon and bone marrow. Not expressed in peripheral blood leukocytes and brain |
| Cellular Localization | Cytoplasm (By similarity). |
| Entrez Gene | 11185 |
|---|---|
| Nucleotide Accession | NP_006765.4 |
Application
INMT Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the INMT antibody detected INMT protein (arrow).
Application
INMT Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the INMT Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
