Application
Western blot analysis of INSC Antibody (Center) in WiDr cell line lysates (35ug/lane). INSC (arrow) was detected using the purified Pab.Application
INSC Antibody (Center) IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the INSC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | INSC Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | INSC; Protein inscuteable homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | INSC Protein inscuteable homolog |
|---|---|
| Molecular Weight(MW) | 63469 Da |
| Function | May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium |
| Tissue Specificity | Isoform 1 is expressed in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas |
| Cellular Localization | Cytoplasm. Note=Localizes to the apical cortex of mitotic epidermal cells and to the apical side of neuronal progenitor cells (By similarity) |
| Entrez Gene | 387755 |
|---|
Application
Western blot analysis of INSC Antibody (Center) in WiDr cell line lysates (35ug/lane). INSC (arrow) was detected using the purified Pab.
Application
INSC Antibody (Center) IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the INSC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
