PPP1R1A, IPP1, Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1
Key Feature
Clonality
Monoclonal
Clone Number
EP902Y
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:100000 IHC
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
IPP1
Alternative Names
PPP1R1A IPP1 Protein phosphatase 1 regulatory subunit 1A Protein phosphatase inhibitor 1
Molecular Weight(MW)
19011 Da
Function
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases
Tissue Specificity
A synthetic peptide corresponding to residues in the N-terminus of human IPP-1 was used as an immunogen.