Application
Western blot analysis of IPPK Antibody (Center) in HL-60 cell line lysates (35ug/lane). IPPK (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with IPPK Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | IPPK Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IPPK; C9orf12; Inositol-pentakisphosphate 2-kinase; IPK1 homolog; Inositol-1, 3, 4, 5, 6-pentakisphosphate 2-kinase; Ins(1, 3, 4, 5, 6)P5 2-kinase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C9orf12 |
|---|---|
| Alternative Names | IPPK C9orf12 Inositol-pentakisphosphate 2-kinase IPK1 homolog Inositol-1 3 4 5 6-pentakisphosphate 2-kinase Ins(1 3 4 5 6)P5 2-kinase |
| Molecular Weight(MW) | 56017 Da |
| Function | Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis |
| Tissue Specificity | Ubiquitously expressed, with high expression in heart, brain, testis and placenta |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity) |
| Entrez Gene | 64768 |
|---|
Application
Western blot analysis of IPPK Antibody (Center) in HL-60 cell line lysates (35ug/lane). IPPK (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with IPPK Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
