Application
IQGAP1 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the IQGAP1 antibody detected the IQGAP1 protein (arrow).| Product Name | IQGAP1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0051 |
|---|---|
| Alternative Names | IQGAP1 KIAA0051 Ras GTPase-activating-like protein IQGAP1 p195 |
| Molecular Weight(MW) | 189252 Da |
| Function | Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth |
| Tissue Specificity | Expressed in the placenta, lung, and kidney. A lower level expression is seen in the heart, liver, skeletal muscle and pancreas |
| Cellular Localization | Cell membrane. |
| Entrez Gene | 8826 |
|---|---|
| Nucleotide Accession | NP_003861.1 |
Application
IQGAP1 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the IQGAP1 antibody detected the IQGAP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
