Application
Western blot analysis of IRF4 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). IRF4 (arrow) was detected using the purified Pab.Application
Western blot analysis of IRF4 (arrow) using rabbit polyclonal IRF4 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IRF4 gene.Application
IRF4 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | IRF4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IRF4; MUM1; Interferon regulatory factor 4; Lymphocyte-specific interferon regulatory factor; Multiple myeloma oncogene 1; NF-EM5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:50~100 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MUM1 |
|---|---|
| Alternative Names | IRF4 MUM1 Interferon regulatory factor 4 Lymphocyte-specific interferon regulatory factor Multiple myeloma oncogene 1 NF-EM5 |
| Molecular Weight(MW) | 51772 Da |
| Function | Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity) |
| Tissue Specificity | Lymphoid cells. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 3662 |
|---|
Application
Western blot analysis of IRF4 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). IRF4 (arrow) was detected using the purified Pab.
Application
Western blot analysis of IRF4 (arrow) using rabbit polyclonal IRF4 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the IRF4 gene.
Application
IRF4 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:50~100 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
