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IRF4 antibody

Catalog Number:OM259947
OM259947
Discount Price
OM259947-100ul
1~2 Week
100ul
OM259947-50ul
50ul
OM259947-20ul
20ul
1~2 Week
Product Profile
Product Name IRF4 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to IRF4 (interferon regulatory factor 4)The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human IRF4. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IPWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity Human
Predicted Reactivity Mouse, Rat, Pig, Chicken, Rhesus Monkey, BovineMouse (91%), Rat (92%), Pig (93%), Chicken (87%), Rhesus Monkey (98%), Bovine (93%)
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms MUM1
interferon regulatory factor 4
LSIRF
NF-EM5
Target IRF4
Cellular Localization Nucleus
Application

Application

IRF4 antibody detects IRF4 protein by Western blot analysis. A. 30 µg NCI-H929 whole cell lysate/extract 10 % SDS-PAGE IRF4 antibody dilution: 1:1000

Application

Immunoprecipitation of IRF4 protein from NCI-H929 whole cell extracts using 5 μg of IRF4 antibody . Western blot analysis was performed using IRF4 antibody . EasyBlot anti-Rabbit IgG was used as a secondary reagent.
Positive Control NCI-H929
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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