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IRF2 Antibody (Center)

Catalog Number:OM236082
OM236082
Discount Price
OM236082-100ul
1~2 Week
100ul
OM236082-50ul
50ul
OM236082-20ul
20ul
1~2 Week
Product Profile
Product Name IRF2 Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias IRF2; Interferon regulatory factor 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names IRF2
Interferon regulatory factor 2
Molecular Weight(MW) 39354 Da
Function Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7 Constitutively binds to the ISRE promoter to activate IL7 Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation
Tissue Specificity Expressed throughout the epithelium of the colon. Also expressed in lamina propria
Cellular Localization Nucleus.
Database Links
Entrez Gene 3660
Nucleotide Accession NP_002190
Application

Application

IRF2 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the IRF2 antibody detected the IRF2 protein (arrow).

Application

IRF2 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the IRF2 antibody detected the IRF2 protein (arrow).
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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