Western blot analysis of anti-IRF6 Antibody (C-term) (RB13814) in CEM cell line lysates (35ug/lane). IRF6(arrow) was detected using the purified Pab (1:60 dilution).
Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity)
Tissue Specificity
Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas
Cellular Localization
Nucleus (Potential). Cytoplasm. Note=Translocates to nucleus in response to an activating signal (By similarity)
Western blot analysis of anti-IRF6 Antibody (C-term) (RB13814) in CEM cell line lysates (35ug/lane). IRF6(arrow) was detected using the purified Pab (1:60 dilution).
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.