Application
A. Western blot analysis of anti-IRR alpha subunit RabMAb (Cat. #AJ1415a), dilution 1:2,000. A: PC12 B: MCF-7 C: Hela D: SHSY5YApplication
B. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IRR alpha subunit RabMAb (Cat. #AJ1415a).| Product Name | IRR alpha Antibody subunit |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | INSRR, IRR, Insulin receptor-related protein beta chain, IR-related receptor |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP327Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~2000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IRR |
|---|---|
| Alternative Names | INSRR IRR Insulin receptor-related protein beta chain IR-related receptor |
| Molecular Weight(MW) | 143720 Da |
| Function | Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB |
| Tissue Specificity | A synthetic peptide corresponding to residues near the N-terminus of human IRR alpha subunit was used as immunogen. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 3645 |
|---|
Application
A. Western blot analysis of anti-IRR alpha subunit RabMAb (Cat. #AJ1415a), dilution 1:2,000. A: PC12 B: MCF-7 C: Hela D: SHSY5Y
Application
B. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IRR alpha subunit RabMAb (Cat. #AJ1415a).| Application Notes | WB:1:1000~2000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
