Application
IRX5 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the IRX5 antibody detected the IRX5 protein (arrow).| Product Name | IRX5 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IRX5; IRX2A; IRXB2; Iroquois-class homeodomain protein IRX-5; Homeodomain protein IRX-2A; Homeodomain protein IRXB2; Iroquois homeobox protein 5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IRX2A IRXB2 |
|---|---|
| Alternative Names | IRX5 IRX2A IRXB2 Iroquois-class homeodomain protein IRX-5 Homeodomain protein IRX-2A Homeodomain protein IRXB2 Iroquois homeobox protein 5 |
| Molecular Weight(MW) | 50361 Da |
| Function | Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. Involved in craniofacial and gonadal development. Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12 |
| Tissue Specificity | This IRX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of human IRX5. |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 10265 |
|---|---|
| Nucleotide Accession | NP_005844.4 |
Application
IRX5 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the IRX5 antibody detected the IRX5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
