Application
IRX3 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the IRX3 antibody detected the IRX3 protein (arrow).Application
IRX3 Antibody (N-term) (AP14549a)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IRX3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | IRX3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IRX3; IRXB1; Iroquois-class homeodomain protein IRX-3; Homeodomain protein IRXB1; Iroquois homeobox protein 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IRXB1 |
|---|---|
| Alternative Names | IRX3 IRXB1 Iroquois-class homeodomain protein IRX-3 Homeodomain protein IRXB1 Iroquois homeobox protein 3 |
| Molecular Weight(MW) | 52119 Da |
| Function | Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity) |
| Tissue Specificity | This IRX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-140 amino acids from the N-terminal region of human IRX3. |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 79191 |
|---|---|
| Nucleotide Accession | NP_077312.2 |
Application
IRX3 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the IRX3 antibody detected the IRX3 protein (arrow).
Application
IRX3 Antibody (N-term) (AP14549a)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IRX3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
