ITGA2 CD49B Integrin alpha-2 CD49 antigen-like family member B Collagen receptor Platelet membrane glycoprotein Ia VLA-2 subunit alpha CD_antigen=CD49b Flags: Precursor
Molecular Weight(MW)
129295 Da
Function
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix
Tissue Specificity
This ITGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1029~1058 amino acids from the C-terminal region of human ITGA2.
Western blot analysis of ITGA2 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). ITGA2 (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.