Application
Western blot analysis of ITGB1BP3 Antibody (N-term) in K562 cell line lysates (35ug/lane). ITGB1BP3 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with ITGB1BP3 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | ITGB1BP3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NMRK2; ITGB1BP3; NRK2; Nicotinamide riboside kinase 2; Integrin beta-1-binding protein 3; Muscle integrin-binding protein; Nicotinic acid riboside kinase 2; Ribosylnicotinamide kinase 2; Ribosylnicotinic acid kinase 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ITGB1BP3 NRK2 |
|---|---|
| Alternative Names | NMRK2 ITGB1BP3 NRK2 Nicotinamide riboside kinase 2 Integrin beta-1-binding protein 3 Muscle integrin-binding protein Nicotinic acid riboside kinase 2 Ribosylnicotinamide kinase 2 Ribosylnicotinic acid kinase 2 |
| Molecular Weight(MW) | 26046 Da |
| Function | Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN) Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis |
| Tissue Specificity | Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta |
| Entrez Gene | 27231 |
|---|
Application
Western blot analysis of ITGB1BP3 Antibody (N-term) in K562 cell line lysates (35ug/lane). ITGB1BP3 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with ITGB1BP3 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
