Application
ITGB1BP1 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ITGB1BP1 antibody detected the ITGB1BP1 protein (arrow).| Product Name | ITGB1BP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ITGB1BP1; ICAP1; Integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ICAP1 |
|---|---|
| Alternative Names | ITGB1BP1 ICAP1 Integrin beta-1-binding protein 1 Integrin cytoplasmic domain-associated protein 1 |
| Molecular Weight(MW) | 21782 Da |
| Function | Regulates integrin signaling by binding to the ITGB1 cytoplasmic tail and preventing the activation of integrin alpha- 5/beta-1 (heterodimer of ITGA5 and ITGB1) by talin or FERMT1. May play a role in the recruitment of ITGB1 to focal contacts during integrin-dependent cell adhesion |
| Tissue Specificity | Expressed in intestine, colon, testis, ovary, thymus, spleen and prostate |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 9270 |
|---|---|
| Nucleotide Accession | NP_004754.1 NP_071729.1 |
Application
ITGB1BP1 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ITGB1BP1 antibody detected the ITGB1BP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
