Application
JAG1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the JAG1 antibody detected the JAG1 protein (arrow).Application
JAG1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | JAG1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | JAG1; JAGL1; Protein jagged-1; CD_antigen=CD339; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | JAGL1 |
|---|---|
| Alternative Names | JAG1 JAGL1 Protein jagged-1 CD_antigen=CD339 Flags: Precursor |
| Molecular Weight(MW) | 133799 Da |
| Function | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro) |
| Tissue Specificity | Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 182 |
|---|---|
| Nucleotide Accession | NP_000205.1 |
Application
JAG1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the JAG1 antibody detected the JAG1 protein (arrow).
Application
JAG1 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
