Application
Western blot analysis of anti-JMJD2D (C-term) Pab in Hela cell line lysate. JMJD2D (C-term)(arrow) was detected using the purified Pab.| Product Name | JMJD2D Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KDM4D; JHDM3D; JMJD2D; Lysine-specific demethylase 4D; JmjC domain-containing histone demethylation protein 3D; Jumonji domain-containing protein 2D |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:250~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | JHDM3D JMJD2D |
|---|---|
| Alternative Names | KDM4D JHDM3D JMJD2D Lysine-specific demethylase 4D JmjC domain-containing histone demethylation protein 3D Jumonji domain-containing protein 2D |
| Molecular Weight(MW) | 58603 Da |
| Function | Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys- 9' residue, while it has no activity on monomethylated residues Demethylation of Lys residue generates formaldehyde and succinate |
| Tissue Specificity | This JMJD2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 493~522 amino acids from the C-terminal region of human JMJD2D. |
| Cellular Localization | Nucleus (By similarity). |
Application
Western blot analysis of anti-JMJD2D (C-term) Pab in Hela cell line lysate. JMJD2D (C-term)(arrow) was detected using the purified Pab.| Application Notes | WB:1:250~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
