Application
K0415 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the K0415 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | K0415 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AP5Z1; KIAA0415; SPG48; AP-5 complex subunit zeta-1; Adapter-related protein complex 5 zeta subunit |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0415 SPG48 |
|---|---|
| Alternative Names | AP5Z1 KIAA0415 SPG48 AP-5 complex subunit zeta-1 Adapter-related protein complex 5 zeta subunit |
| Molecular Weight(MW) | 88605 Da |
| Function | As part of AP-5, a probable fifth adapter protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair |
| Tissue Specificity | This K0415 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 302-332 amino acids from the Central region of human K0415. |
| Cellular Localization | Cytoplasm. Nucleus. Note=By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic (PubMed:20613862) |
| Entrez Gene | 9907 |
|---|
Application
K0415 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the K0415 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | IHC:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
