Application
KAZ Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KAZ antibody detected the KAZ protein (arrow).| Product Name | KAZ Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KAZN; KAZ; KIAA1026; Kazrin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KAZ KIAA1026 |
|---|---|
| Alternative Names | KAZN KAZ KIAA1026 Kazrin |
| Molecular Weight(MW) | 86351 Da |
| Function | Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known |
| Tissue Specificity | Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level) |
| Cellular Localization | Cytoplasm, cytoskeleton (By similarity). Isoform 3: Cytoplasm. Cell junction, desmosome. Nucleus. Note=Observed at the apical plasma mebrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane Colocalizes with cortical actin-based membrane structures |
| Entrez Gene | 23254 |
|---|---|
| Nucleotide Accession | NP_001017999.1 |
Application
KAZ Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KAZ antibody detected the KAZ protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
