KAT2A Antibody (C-term) western blot analysis in UM cell line lysates (35ug/lane).This demonstrates the KAT2A antibody detected the KAT2A protein (arrow).
KAT2A; GCN5; GCN5L2; HGCN5; Histone acetyltransferase KAT2A; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; Lysine acetyltransferase 2A; STAF97
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
GCN5 GCN5L2 HGCN5
Alternative Names
KAT2A GCN5 GCN5L2 HGCN5 Histone acetyltransferase KAT2A General control of amino acid synthesis protein 5-like 2 Histone acetyltransferase GCN5 Lysine acetyltransferase 2A STAF97
Molecular Weight(MW)
93926 Da
Function
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4
Tissue Specificity
Expressed in all tissues tested, with most abundant expression in ovary
KAT2A Antibody (C-term) western blot analysis in UM cell line lysates (35ug/lane).This demonstrates the KAT2A antibody detected the KAT2A protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.