Application
KATNB1 Antibody (Center) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the KATNB1 antibody detected the KATNB1 protein (arrow).| Product Name | KATNB1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KATNB1; Katanin p80 WD40-containing subunit B1; p80 katanin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KATNB1 Katanin p80 WD40-containing subunit B1 p80 katanin |
|---|---|
| Molecular Weight(MW) | 72334 Da |
| Function | Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth (By similarity) |
| Tissue Specificity | This KATNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-359 amino acids from the Central region of human KATNB1. |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton. Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles |
| Entrez Gene | 10300 |
|---|---|
| Nucleotide Accession | NP_005877.2 |
Application
KATNB1 Antibody (Center) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the KATNB1 antibody detected the KATNB1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
