Application
KCNJ12 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the KCNJ12 antibody detected the KCNJ12 protein (arrow).| Product Name | KCNJ12 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCNJ12; IRK2; KCNJN1; ATP-sensitive inward rectifier potassium channel 12; Inward rectifier K(+) channel Kir2.2; Inward rectifier K(+) channel Kir2.2v; Potassium channel, inwardly rectifying subfamily J member 12 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IRK2 KCNJN1 |
|---|---|
| Alternative Names | KCNJ12 IRK2 KCNJN1 ATP-sensitive inward rectifier potassium channel 12 Inward rectifier K(+) channel Kir2.2 Inward rectifier K(+) channel Kir2.2v Potassium channel inwardly rectifying subfamily J member 12 |
| Molecular Weight(MW) | 49001 Da |
| Function | Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium |
| Tissue Specificity | This KCNJ12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-433 amino acids from the C-terminal region of human KCNJ12. |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 3768 |
|---|---|
| Nucleotide Accession | NP_066292.2 |
Application
KCNJ12 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the KCNJ12 antibody detected the KCNJ12 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
