Application
KCNJ13 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the KCNJ13 antibody detected the KCNJ13 protein (arrow).Application
KCNJ13 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNJ13 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | KCNJ13 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCNJ13; Inward rectifier potassium channel 13; Inward rectifier K(+) channel Kir7.1; Potassium channel, inwardly rectifying subfamily J member 13 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KCNJ13 Inward rectifier potassium channel 13 Inward rectifier K(+) channel Kir7.1 Potassium channel inwardly rectifying subfamily J member 13 |
|---|---|
| Molecular Weight(MW) | 40530 Da |
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium |
| Tissue Specificity | Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 3769 |
|---|---|
| Nucleotide Accession | NP_002233.2 NP_001165887.1 |
Application
KCNJ13 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the KCNJ13 antibody detected the KCNJ13 protein (arrow).
Application
KCNJ13 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNJ13 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
