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KCNJ4 Antibody (N-term)

Catalog Number:OM236449
OM236449
Discount Price
OM236449-100ul
1~2 Week
100ul
OM236449-50ul
50ul
OM236449-20ul
20ul
1~2 Week
Product Profile
Product Name KCNJ4 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias KCNJ4; IRK3; Inward rectifier potassium channel 4; HIRK2; HRK1; Hippocampal inward rectifier; Inward rectifier K(+) channel Kir2.3; Potassium channel, inwardly rectifying subfamily J member 4
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms IRK3
Alternative Names KCNJ4
IRK3
Inward rectifier potassium channel 4
HIRK2
HRK1
Hippocampal inward rectifier
Inward rectifier K(+) channel Kir2.3
Potassium channel
inwardly rectifying subfamily J member 4
Molecular Weight(MW) 49500 Da
Function This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity)
Tissue Specificity Heart, skeletal muscle, and several different brain regions including the hippocampus
Cellular Localization Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane (By similarity). Note=TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 famaly members and KCNJ4 internalization (By similarity)
Database Links
Entrez Gene 3761
Nucleotide Accession NP_690607.1 NP_004972.1
Application

Application

KCNJ4 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the KCNJ4 antibody detected the KCNJ4 protein (arrow).
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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