Application
KCNJ8 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the KCNJ8 antibody detected the KCNJ8 protein (arrow).Application
KCNJ8 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNJ8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | KCNJ8 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCNJ8; ATP-sensitive inward rectifier potassium channel 8; Inward rectifier K(+) channel Kir6.1; Potassium channel, inwardly rectifying subfamily J member 8; uKATP-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KCNJ8 ATP-sensitive inward rectifier potassium channel 8 Inward rectifier K(+) channel Kir6.1 Potassium channel inwardly rectifying subfamily J member 8 uKATP-1 |
|---|---|
| Molecular Weight(MW) | 47968 Da |
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity) |
| Tissue Specificity | Predominantly detected in fetal and adult heart |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 3764 |
|---|---|
| Nucleotide Accession | NP_004973.1 |
Application
KCNJ8 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the KCNJ8 antibody detected the KCNJ8 protein (arrow).
Application
KCNJ8 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCNJ8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
