Application
Western blot analysis of KCTD12 Antibody (Center) in T47D cell line lysates (35ug/lane). KCTD12 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with KCTD12 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
KCTD12 Antibody (Center) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | KCTD12 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCTD12; C13orf2; KIAA1778; PFET1; BTB/POZ domain-containing protein KCTD12; Pfetin; Predominantly fetal expressed T1 domain |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C13orf2 KIAA1778 PFET1 |
|---|---|
| Alternative Names | KCTD12 C13orf2 KIAA1778 PFET1 BTB/POZ domain-containing protein KCTD12 Pfetin Predominantly fetal expressed T1 domain |
| Molecular Weight(MW) | 35701 Da |
| Function | Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity) |
| Tissue Specificity | Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung |
| Cellular Localization | Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane (By similarity) |
| Entrez Gene | 115207 |
|---|
Application
Western blot analysis of KCTD12 Antibody (Center) in T47D cell line lysates (35ug/lane). KCTD12 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with KCTD12 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
KCTD12 Antibody (Center) flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
