Application
KCNT2 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the KCNT2 antibody detected the KCNT2 protein (arrow).Application
KCNT2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KCNT2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
KCNT2 Antibody (C-term) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | KCNT2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCNT2; SLICK; Potassium channel subfamily T member 2; Sequence like an intermediate conductance potassium channel subunit; Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SLICK |
|---|---|
| Alternative Names | KCNT2 SLICK Potassium channel subfamily T member 2 Sequence like an intermediate conductance potassium channel subunit Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1 |
| Molecular Weight(MW) | 130501 Da |
| Function | Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels. Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1 |
| Tissue Specificity | This KCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1076-1105 amino acids from the C-terminal region of human KCNT2. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (By similarity) |
| Entrez Gene | 343450 |
|---|---|
| Nucleotide Accession | NP_940905.2 |
Application
KCNT2 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the KCNT2 antibody detected the KCNT2 protein (arrow).
Application
KCNT2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KCNT2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
KCNT2 Antibody (C-term) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
