Application
KCNV1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the KCNV1 antibody detected KCNV1 protein (arrow).Application
KCNV1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KCNV1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
KCNV1 Antibody (N-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | KCNV1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KCNV1; Potassium voltage-gated channel subfamily V member 1; Neuronal potassium channel alpha subunit HNKA; Voltage-gated potassium channel subunit Kv8.1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KCNV1 Potassium voltage-gated channel subfamily V member 1 Neuronal potassium channel alpha subunit HNKA Voltage-gated potassium channel subunit Kv8.1 |
|---|---|
| Molecular Weight(MW) | 56304 Da |
| Function | Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes |
| Tissue Specificity | Detected in brain. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Note=Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2 |
| Entrez Gene | 27012 |
|---|---|
| Nucleotide Accession | NP_055194.1 |
Application
KCNV1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the KCNV1 antibody detected KCNV1 protein (arrow).
Application
KCNV1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KCNV1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
KCNV1 Antibody (N-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
