KDM6B Antibody (N-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the KDM6B antibody detected the KDM6B protein (arrow).
KDM6B; JMJD3; KIAA0346; Lysine-specific demethylase 6B; JmjC domain-containing protein 3; Jumonji domain-containing protein 3; Lysine demethylase 6B
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
JMJD3 KIAA0346
Alternative Names
KDM6B JMJD3 KIAA0346 Lysine-specific demethylase 6B JmjC domain-containing protein 3 Jumonji domain-containing protein 3 Lysine demethylase 6B
Molecular Weight(MW)
176632 Da
Function
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation
Tissue Specificity
This KDM6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-195 amino acids from the N-terminal region of human KDM6B.
KDM6B Antibody (N-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the KDM6B antibody detected the KDM6B protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.