Application
KHDRBS3 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KHDRBS3 antibody detected the KHDRBS3 protein (arrow).| Product Name | KHDRBS3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KHDRBS3; SALP; SLM2; KH domain-containing, RNA-binding, signal transduction-associated protein 3; RNA-binding protein T-Star; Sam68-like mammalian protein 2; Sam68-like phosphotyrosine protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | SALP SLM2 |
|---|---|
| Alternative Names | KHDRBS3 SALP SLM2 KH domain-containing RNA-binding signal transduction-associated protein 3 RNA-binding protein T-Star Sam68-like mammalian protein 2 Sam68-like phosphotyrosine protein |
| Molecular Weight(MW) | 38800 Da |
| Function | RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA- binding abilities are down-regulated by tyrosine kinase PTK6 Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro |
| Tissue Specificity | Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis |
| Cellular Localization | Nucleus. Note=Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one |
| Entrez Gene | 10656 |
|---|---|
| Nucleotide Accession | NP_006549.1 |
Application
KHDRBS3 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KHDRBS3 antibody detected the KHDRBS3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
