Application
KIAA0319 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KIAA0319 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
KIAA0319 Antibody (C-term) western blot analysis in MDA-MB453,A549 cell line lysates (35ug/lane).This demonstrates the KIAA0319 antibody detected the KIAA0319 protein (arrow).| Product Name | KIAA0319 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KIAA0319; Dyslexia-associated protein KIAA0319 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:10~50 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KIAA0319 Dyslexia-associated protein KIAA0319 |
|---|---|
| Molecular Weight(MW) | 117763 Da |
| Function | Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non- cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites |
| Tissue Specificity | Detected in adult brain cortex and fetal frontal lobe (at protein level). Highly expressed in brain cortex, putamen, amygdala, hippocampus and cerebellum |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Note=Low-abundance isoforms lacking the transmembrane domain have been described; these are secreted |
| Entrez Gene | 9856 |
|---|---|
| Nucleotide Accession | NP_001161846.1 NP_001161847.1 |
Application
KIAA0319 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KIAA0319 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
KIAA0319 Antibody (C-term) western blot analysis in MDA-MB453,A549 cell line lysates (35ug/lane).This demonstrates the KIAA0319 antibody detected the KIAA0319 protein (arrow).| Application Notes | IHC:1:10~50 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
