Application
KIF16b Antibody western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KIF16b antibody detected the KIF16b protein (arrow).Application
KIF16b Antibody (AP15010a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KIF16b Antibody for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | KIF16b Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KIF16B; C20orf23; KIAA1590; SNX23; Kinesin-like protein KIF16B; Sorting nexin-23 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C20orf23 KIAA1590 SNX23 |
|---|---|
| Alternative Names | KIF16B C20orf23 KIAA1590 SNX23 Kinesin-like protein KIF16B Sorting nexin-23 |
| Molecular Weight(MW) | 152011 Da |
| Function | Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development |
| Tissue Specificity | Primarily expressed in brain. Also present in kidney, liver, intestine, placenta, leukocytes, heart and skeletal muscle (at protein level) |
| Cellular Localization | Cytoplasm, cytoskeleton (Probable). Early endosome membrane. Note=It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14 |
| Entrez Gene | 55614 |
|---|---|
| Nucleotide Accession | NP_078980.3 |
Application
KIF16b Antibody western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KIF16b antibody detected the KIF16b protein (arrow).
Application
KIF16b Antibody (AP15010a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KIF16b Antibody for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
