Application
KIF24 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the KIF24 antibody detected KIF24 protein (arrow).Application
KIF24 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KIF24 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
KIF24 Antibody (N-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | KIF24 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KIF24; C9orf48; Kinesin-like protein KIF24 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C9orf48 |
|---|---|
| Alternative Names | KIF24 C9orf48 Kinesin-like protein KIF24 |
| Molecular Weight(MW) | 151903 Da |
| Function | Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress abberrant cilia formation |
| Tissue Specificity | This KIF24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-392 amino acids from the N-terminal region of human KIF24. |
| Cellular Localization | Cytoplasm, cytoskeleton, centrosome, centriole. Note=Primarily localizes to the mother centriole/basal body and is either absent at daughter centriole |
| Entrez Gene | 347240 |
|---|---|
| Nucleotide Accession | NP_919289.2 |
Application
KIF24 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the KIF24 antibody detected KIF24 protein (arrow).
Application
KIF24 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KIF24 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
KIF24 Antibody (N-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
