Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance
Tissue Specificity
This KIFC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200~230 amino acids from the N-terminal region of human KIFC3.
Cellular Localization
Cell junction, adherens junction. Cytoplasm, cytoskeleton, centrosome. Cytoplasmic vesicle membrane; Peripheral membrane protein (By similarity). Note=Apical cell membrane. On membrane organelles immediately beneath the apical plasma membrane of renal tubular epithelial cells. Localized in the distal tubules and loops of Henle in the kidney, but not in the proximal tubules or the glomeruli, with stronger staining in the apical area of these epithelial cells (By similarity). Localizes along zonula adherens only at mature cell-cell contacts
Western blot analysis of KIFC3 Antibody (N-term) (RB24732) in A375 cell line lysates (35ug/lane).KIFC3 (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.