Application
KLHL3 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the KLHL3 antibody detected the KLHL3 protein (arrow).| Product Name | KLHL3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1129 |
|---|---|
| Alternative Names | KLHL3 KIAA1129 Kelch-like protein 3 |
| Molecular Weight(MW) | 64970 Da |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex may act by mediating ubiquitination of SLC12A3/NCC, thereby regulating SLC12A3/NCC subcellular location at the cell membrane |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cytoplasm, cytoskeleton. Cytoplasm, cytosol. |
| Entrez Gene | 26249 |
|---|---|
| Nucleotide Accession | NP_059111.2 |
Application
KLHL3 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the KLHL3 antibody detected the KLHL3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
