Application
KREMEN2 Antibody (Center) western blot analysis in ZR-75-1,K562,NCI-H460 cell line lysates (35ug/lane).This demonstrates the KREMEN2 antibody detected the KREMEN2 protein (arrow).| Product Name | KREMEN2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KREMEN2; KRM2; Kremen protein 2; Dickkopf receptor 2; Kringle domain-containing transmembrane protein 2; Kringle-containing protein marking the eye and the nose |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KRM2 |
|---|---|
| Alternative Names | KREMEN2 KRM2 Kremen protein 2 Dickkopf receptor 2 Kringle domain-containing transmembrane protein 2 Kringle-containing protein marking the eye and the nose |
| Molecular Weight(MW) | 48849 Da |
| Function | Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane (By similarity) |
| Tissue Specificity | This KREMEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the Central region of human KREMEN2. |
| Cellular Localization | Membrane; Single-pass type I membrane protein (Potential) |
| Entrez Gene | 79412 |
|---|---|
| Nucleotide Accession | NP_757384.1 NP_078783.1 |
Application
KREMEN2 Antibody (Center) western blot analysis in ZR-75-1,K562,NCI-H460 cell line lysates (35ug/lane).This demonstrates the KREMEN2 antibody detected the KREMEN2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
