KRT19; Keratin, type I cytoskeletal 19; Cytokeratin-19; Keratin-19
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:50~100
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
KRT19 Keratin type I cytoskeletal 19 Cytokeratin-19 Keratin-19
Molecular Weight(MW)
44106 Da
Function
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle
Tissue Specificity
Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin
Western blot analysis of anti-KRT19 Antibody (S46) in T47D cell line lysates (35ug/lane). KRT19(arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.