Application
KRT74 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the KRT74 antibody detected the KRT74 protein (arrow).Application
KRT74 Antibody (C-term) (AP14878b)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KRT74 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | KRT74 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KRT74; K6IRS4; KB37; KRT5C; KRT6IRS4; Keratin, type II cytoskeletal 74; Cytokeratin-74; Keratin-5c; Keratin-74; Type II inner root sheath-specific keratin-K6irs4; Type-II keratin Kb37 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | K6IRS4 KB37 KRT5C KRT6IRS4 |
|---|---|
| Alternative Names | KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 Keratin type II cytoskeletal 74 Cytokeratin-74 Keratin-5c Keratin-74 Type II inner root sheath-specific keratin-K6irs4 Type-II keratin Kb37 |
| Molecular Weight(MW) | 57865 Da |
| Function | Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable) |
| Tissue Specificity | Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS Huxley layer, but not in Henle layer or cuticle of the IRS. In the IRS Huxley layer, it is expressed in specialized Huxley cells, termed 'Fluegelzellen, along the area of differentiated Henle cells (at protein level) |
| Entrez Gene | 121391 |
|---|---|
| Nucleotide Accession | NP_778223.2 |
Application
KRT74 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the KRT74 antibody detected the KRT74 protein (arrow).
Application
KRT74 Antibody (C-term) (AP14878b)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KRT74 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
