KCND2, KIAA1044, Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2
Key Feature
Clonality
Monoclonal
Clone Number
EP982Y
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:1000 IHC
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
KIAA1044
Alternative Names
KCND2 KIAA1044 Potassium voltage-gated channel subfamily D member 2 Voltage-gated potassium channel subunit Kv4.2
Molecular Weight(MW)
70537 Da
Function
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits
Tissue Specificity
Highly expressed throughout the brain. Expression is very low or absent in other tissues
Cellular Localization
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Detected in dendrites in cultured hippocampal neurons. Association with KCNIP2 probably enhances cell surface expression