Application
LAS1L Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LAS1L antibody detected the LAS1L protein (arrow).| Product Name | LAS1L Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LAS1L; Ribosomal biogenesis protein LAS1L; Protein LAS1 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | LAS1L Ribosomal biogenesis protein LAS1L Protein LAS1 homolog |
|---|---|
| Molecular Weight(MW) | 83065 Da |
| Function | Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes |
| Tissue Specificity | This LAS1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 638-665 amino acids from the C-terminal region of human LAS1L. |
| Cellular Localization | Nucleus, nucleolus. Nucleus, nucleoplasm (By similarity). Cytoplasm (By similarity). Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export |
| Entrez Gene | 81887 |
|---|---|
| Nucleotide Accession | NP_001164120.1 NP_001164121.1 |
Application
LAS1L Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LAS1L antibody detected the LAS1L protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
