Application
LAT2 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LAT2 antibody detected the LAT2 protein (arrow).| Product Name | LAT2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LAT2; LAB; NTAL; WBS15; WBSCR15; WBSCR5; Linker for activation of T-cells family member 2; Linker for activation of B-cells; Membrane-associated adapter molecule; Non-T-cell activation linker; Williams-Beuren syndrome chromosomal region 15 protein; William |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LAB NTAL WBS15 WBSCR15 WBSCR5 |
|---|---|
| Alternative Names | LAT2 LAB NTAL WBS15 WBSCR15 WBSCR5 Linker for activation of T-cells family member 2 Linker for activation of B-cells Membrane-associated adapter molecule Non-T-cell activation linker Williams-Beuren syndrome chromosomal region 15 protein William |
| Molecular Weight(MW) | 26550 Da |
| Function | Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2 |
| Tissue Specificity | Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B- cells, NK cells and monocytes. Absent from T-cells (at protein level) |
| Cellular Localization | Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts |
| Entrez Gene | 7462 |
|---|---|
| Nucleotide Accession | NP_054865.2 NP_115852.1 |
Application
LAT2 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LAT2 antibody detected the LAT2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
