Subcellular localization of NTAL by confocal microscopy in the myeloid cell line THP-1. THP-1 cells were permeabilized and immunostained using antibody NAP-07 (green). Nuclei are vizualized by propidium iodide (red).
Mouse monoclonal [NAP - 07] to NTALThis gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq]
Immunogen
Recombinant fragment, corresponding to amino acids 91-244 of Human NTAL.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
NAP-07
Host Species
Mouse
Tested Applications
ICC/IFIPWB
IF: Use at an assay dependant concentration. (See reference listed). IP: Use at an assay dependant concentration. WB: Use at an assay dependant concentration. Use non-reducing conditions. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
LAB NTAL WBSCR15 WBSCR5 WSCR5
Target
NTAL
Tissue Specificity
The antibody reacts with Non-T cell activation linker (NTAL) a 30 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells.
Application
Application
Subcellular localization of NTAL by confocal microscopy in the myeloid cell line THP-1. THP-1 cells were permeabilized and immunostained using antibody NAP-07 (green). Nuclei are vizualized by propidium iodide (red).
Application Notes
IF: Use at an assay dependant concentration. (See reference listed). IP: Use at an assay dependant concentration. WB: Use at an assay dependant concentration. Use non-reducing conditions. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.