Application
LCLT1 Antibody (C-term) western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the LCLT1 antibody detected LCLT1 protein (arrow).Application
LCLT1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LCLT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | LCLT1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LCLAT1; AGPAT8; ALCAT1; LYCAT; Lysocardiolipin acyltransferase 1; 1-acylglycerol-3-phosphate O-acyltransferase 8; Acyl-CoA:lysocardiolipin acyltransferase 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AGPAT8 ALCAT1 LYCAT |
|---|---|
| Alternative Names | LCLAT1 AGPAT8 ALCAT1 LYCAT Lysocardiolipin acyltransferase 1 1-acylglycerol-3-phosphate O-acyltransferase 8 Acyl-CoA:lysocardiolipin acyltransferase 1 |
| Molecular Weight(MW) | 48920 Da |
| Function | Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity Required for establishment of the hematopoietic and endothelial lineages |
| Tissue Specificity | Expressed at higher level in heart, kidney and pancreas than in brain, spleen, liver, lung, small intestine and placenta |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Entrez Gene | 253558 |
|---|---|
| Nucleotide Accession | NP_872357.2 |
Application
LCLT1 Antibody (C-term) western blot analysis in mouse kidney tissue lysates (15ug/lane).This demonstrates the LCLT1 antibody detected LCLT1 protein (arrow).
Application
LCLT1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LCLT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
