Application
LCP1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the LCP1 antibody detected the LCP1 protein (arrow).| Product Name | LCP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LCP1; PLS2; Plastin-2; L-plastin; LC64P; Lymphocyte cytosolic protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PLS2 |
|---|---|
| Alternative Names | LCP1 PLS2 Plastin-2 L-plastin LC64P Lymphocyte cytosolic protein 1 |
| Molecular Weight(MW) | 70288 Da |
| Function | Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69 |
| Tissue Specificity | Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells |
| Cellular Localization | Cytoplasm, cytoskeleton. Cell junction. Cell projection. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28. Associated with the actin cytoskeleton at membrane ruffles (By similarity). Relocalizes to actin-rich cell projections upon serine phosphorylation |
| Entrez Gene | 3936 |
|---|---|
| Nucleotide Accession | NP_002289.2 |
Application
LCP1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the LCP1 antibody detected the LCP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
