Application
Western blot analysis of LDLR Antibody (Center) in mouse lung tissue lysates (35ug/lane). LDLR (arrow) was detected using the purified Pab.Application
LDLR Antibody (Center) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | LDLR Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LDLR; Low-density lipoprotein receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | LDLR Low-density lipoprotein receptor |
|---|---|
| Molecular Weight(MW) | 95376 Da |
| Function | Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells |
| Tissue Specificity | This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398~427 amino acids from the Center region of human LDLR. |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Endomembrane system; Single-pass type I membrane protein Membrane, clathrin-coated pit; Single-pass type I membrane protein. Golgi apparatus. Early endosome. Late endosome. Cell surface. Lysosome. Note=Found distributed from the plasma membrane to intracellular compartments. Localizes to the Golgi apparatus, early and late endosomes/lysosomes and cell surface in the presence of PCSK9 |
| Entrez Gene | 3949 |
|---|
Application
Western blot analysis of LDLR Antibody (Center) in mouse lung tissue lysates (35ug/lane). LDLR (arrow) was detected using the purified Pab.
Application
LDLR Antibody (Center) FC analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
