Application
LILRB4 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the LILRB4 antibody detected the LILRB4 protein (arrow).| Product Name | LILRB4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LILRB4; ILT3; LIR5; Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85 antigen-like family member K; Immunoglobulin-like transcript 3; Leukocyte immunoglobulin-like receptor 5; Monocyte inhibitory receptor HM18; CD_antigen=CD85k; Flags: Prec |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ILT3 LIR5 |
|---|---|
| Alternative Names | LILRB4 ILT3 LIR5 Leukocyte immunoglobulin-like receptor subfamily B member 4 CD85 antigen-like family member K Immunoglobulin-like transcript 3 Leukocyte immunoglobulin-like receptor 5 Monocyte inhibitory receptor HM18 CD_antigen=CD85k Flags: Prec |
| Molecular Weight(MW) | 49356 Da |
| Function | Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5- signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions |
| Tissue Specificity | Detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment |
| Entrez Gene | 11006 |
|---|---|
| Nucleotide Accession | NP_006838.3 NP_001074907.1 |
Application
LILRB4 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the LILRB4 antibody detected the LILRB4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
