Application
LIG4 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the LIG4 antibody detected the LIG4 protein (arrow).| Product Name | LIG4 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LIG4;DNA ligase 4; DNA ligase 4; DNA ligase IV; DNA ligase 4; Polydeoxyribonucleotide synthase [ATP] 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | LIG4 DNA ligase 4 DNA ligase 4 DNA ligase IV DNA ligase 4 Polydeoxyribonucleotide synthase [ATP] 4 |
|---|---|
| Molecular Weight(MW) | 103971 Da |
| Function | Efficiently joins single-strand breaks in a double- stranded polydeoxynucleotide in an ATP-dependent reaction Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA- dependent protein kinase complex DNA-PK to these DNA ends |
| Tissue Specificity | Testis, thymus, prostate and heart. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 3981 |
|---|
Application
LIG4 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the LIG4 antibody detected the LIG4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
