Application
LIME1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the LIME1 antibody detected the LIME1 protein (arrow).| Product Name | LIME1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LIME1; LIME; Lck-interacting transmembrane adapter 1; Lck-interacting molecule |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LIME |
|---|---|
| Alternative Names | LIME1 LIME Lck-interacting transmembrane adapter 1 Lck-interacting molecule |
| Molecular Weight(MW) | 31288 Da |
| Function | Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules |
| Tissue Specificity | Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level) |
| Cellular Localization | Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen- presenting cell |
| Entrez Gene | 54923 |
|---|---|
| Nucleotide Accession | NP_060276.2 |
Application
LIME1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the LIME1 antibody detected the LIME1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
